WORLD CLASS RESEARCH MAKING A DIFFERENCE – Expanded Newborn Screening #CLAHRCS @sheffchildrens

Expanded Newborn Screening (ENBS) – CLAHRC Yorkshire and Humber

  • Newborn screening extended to cover four new conditions
  • Estimated 20 to 30 lives saved per year
  • ‘Second chance’ for baby treated for life-threatening illness picked up by screening process

Identifying metabolic diseases at birth is crucial to early treatment and the ability to save lives.
The Expanded Newborn Screening (ENBS) project funded by CLAHRC Yorkshire and Humber (formerly CLAHRC South Yorkshire) involved screening 430,000 infants for five metabolic disorders in addition to the five conditions that are currently usual practice. Health economic analysis of the project predicted that national screening for these conditions would be cost-effective. During the project, 12 patients were detected as having one of the inherited metabolic diseases, thus allowing for treatment to start sooner than otherwise would have been possible and improving the life and wellbeing of these children and their families.

National Screening Committee

Clinical and health economic evidence was submitted to satisfy the National Screening Committee that expanding the existing national screening programme was appropriate. As a consequence, children born since January 2015 are now screened for a further four conditions. Around 700,000 children are born in England each year and expanded screening is estimated to offer significant health benefits as well as potentially saving the lives of 20 to 30 children per year.

Project summary
What? – Expanded Newborn Screening (ENBS) is a study that looked into expanding tests at birth to identify five metabolic disorders in addition to the five conditions currently tested.
Why? – Expanding the newborn screening saves infant lives as well as being cost-effective.
How? – The project involved screening 430,000 infants to justify a national screening.

Result Project presented clinical and health economic evidence to the National Screening Committee, who then expanded the national screening programme. It is estimated that this health benefit will save approximately 20 to 30 infant lives each year.

Case study taken from the CLAHRCs Impact document  World class research making a difference

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s